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What Causes Uneven Breasts? Lopsided breasts, or very uneven breasts, are known in the medical world as breast asymmetry. Your breasts can grow to appear this way due to several different possibilities: Uneven adolescence development Virginal hypertrophy following puberty Pregnancy Breastfeeding Breast Infection Aging Shrinkage caused by a medical condition Weight change Mastectomy Previously-botched breast augmentation How Common Are Crooked
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